Telomerase inhibitor GRN163L inhibits myeloma cell growth in vitro and in vivo

Human telomerase, the reverse transcriptase which extends the life span of a cell by adding telomeric repeats to chromosome ends, is expressed in most cancer cells but not in the majority of normal somatic cells. Inhibition of telomerase therefore holds great promise as anticancer therapy. We have s...

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書誌詳細
主要な著者: Shammas, MA, Koley, H, Bertheau, RC, Neri, P, Fulciniti, M, Tassone, P, Blotta, S, Protopopov, A, Mitsiades, C, Batchu, RB, Anderson, KC, Chin, A, Gryaznov, S, Munshi, NC
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155939/
https://ncbi.nlm.nih.gov/pubmed/18449204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2008.81
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