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Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts
Telomerase is a ribonucleoprotein complex that elongates telomeric DNA and appears to play an important role in cellular immortalization of cancers. Because telomerase is expressed in the vast majority of malignant gliomas but not in normal brain tissues, it is a logical target for glioma-specific t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Duke University Press
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1871998/ https://ncbi.nlm.nih.gov/pubmed/15279714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/S1152851704000055 |
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