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Influence of aging and hemorrhage injury on Sirt1 expression: Possible role of myc-Sirt1 regulation in mitochondrial function

Trauma-hemorrhage (T-H) causes hypoxia and organ dysfunction. Mitochondrial dysfunction is a major factor for cellular injury due to T-H. Aging also has been known to cause progressive mitochondrial dysfunction. In order to study the effect of aging on T-H-induced mitochondrial dysfunction, we recen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jian, Bixi, Yang, Shaolong, Chen, Dongquan, Chaudry, Irshad, Raju, Raghavan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155671/
https://ncbi.nlm.nih.gov/pubmed/21554952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2011.04.010
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