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Resveratrol Restores Sirtuin 1 (SIRT1) Activity and Pyruvate Dehydrogenase Kinase 1 (PDK1) Expression after Hemorrhagic Injury in a Rat Model

Severe hemorrhage leads to decreased blood flow to tissues resulting in decreased oxygen and nutrient availability affecting mitochondrial function. A mitoscriptome profiling study demonstrated alteration in several genes related to mitochondria, consistent with the mitochondrial functional decline...

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Hlavní autoři: Jian, Bixi, Yang, Shaolong, Chaudry, Irshad H, Raju, Raghavan
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912254/
https://ncbi.nlm.nih.gov/pubmed/24395567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2013.00077
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