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Signaling through the IL-2 receptor γ(c) peptide (CD132) is essential for the expression of immunity to Plasmodium chabaudi adami blood-stage malaria

A genetic dissection approach was employed to determine whether the IL-2 receptor complex (IL-2R) comprised of α, β and γ chains is required for the suppression of Plasmodium chabaudi adami parasitemia. Blood-stage infections in IL-2Rγ(c)(-/y) mice failed to cure with parasitemia remaining elevated...

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Bibliografische gegevens
Hoofdauteurs: Weidanz, William P, LaFleur, GayeLyn, Kita-Yarbro, Amanda, Nelson, Katharine, Burns, J. M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155670/
https://ncbi.nlm.nih.gov/pubmed/21585397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-3024.2011.01298.x
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