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Taxol arrests the development of blood-stage Plasmodium falciparum in vitro and Plasmodium chabaudi adami in malaria-infected mice.

Taxol, a natural product used to treat a variety of human cancers, is shown here to be extremely effective against chloroquine- and pyrimethamine-resistant malaria parasites. Addition of Taxol (1.0 microM) for one cycle to cultures of human erythrocytes infected with Plasmodium falciparum prevents t...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Pouvelle, B, Farley, P J, Long, C A, Taraschi, T F
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296324/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7913713/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117338
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