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Opioid antinociception, tolerance and dependence: Interactions with the N-methyl-d-aspartate (NMDA) system in mice
This study explored the involvement of N-methyl-D-aspartate (NMDA) in the effects of mu opioid agonists. A hot plate procedure was used to assess antinociception and tolerance in mice in which the NR1 subunit of the NMDA receptor was reduced (knocked down, KD) to approximately 10% and in mice treate...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155647/ https://ncbi.nlm.nih.gov/pubmed/21712708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e328348ed08 |
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