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Benzene toxicity: The role of the susceptibility factor NQO1 in bone marrow endothelial cell signaling and function
The homozygous NQO1*2 polymorphism results in a null NQO1 phenotype and is a susceptibility factor for occupational benzene poisoning. NQO1 plays an important role in detoxification of benzene-derived quinones but plays a role in numerous other non-metabolic cellular functions. NQO1 is expressed in...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155573/ https://ncbi.nlm.nih.gov/pubmed/20970411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.10.008 |
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