Benzene Metabolite Hydroquinone Up-Regulates Chondromodulin-I and Inhibits Tube Formation in Human Bone Marrow Endothelial Cells

Bone marrow is a major target of benzene toxicity, and NAD- (P)H:quinone oxidoreductase (NQO1), an enzyme protective against benzene toxicity, is present in human bone marrow endothelial cells, which form the hematopoietic stem cell vascular niche. In this study, we have employed a transformed human...

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Autori principali: Zhou, Hongfei, Kepa, Jadwiga K., Siegel, David, Miura, Shigenori, Hiraki, Yuji, Ross, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730389/
https://ncbi.nlm.nih.gov/pubmed/19525446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.057323
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