Nav1.9 Channel Contributes to Mechanical and Heat Pain Hypersensitivity Induced by Subacute and Chronic Inflammation

Inflammation is known to be responsible for the sensitization of peripheral sensory neurons, leading to spontaneous pain and invalidating pain hypersensitivity. Given its role in regulating neuronal excitability, the voltage-gated Nav1.9 channel is a potential target for the treatment of pathologica...

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Main Authors: Lolignier, Stéphane, Amsalem, Muriel, Maingret, François, Padilla, Françoise, Gabriac, Mélanie, Chapuy, Eric, Eschalier, Alain, Delmas, Patrick, Busserolles, Jérôme
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155549/
https://ncbi.nlm.nih.gov/pubmed/21857998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023083
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