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Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors

Cold hypersensitivity is the hallmark of oxaliplatin-induced neuropathy, which develops in nearly all patients under this chemotherapy. To date, pain management strategies have failed to alleviate these symptoms, hence development of adapted analgesics is needed. Here, we report that oxaliplatin exa...

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Detalhes bibliográficos
Main Authors: Descoeur, Juliette, Pereira, Vanessa, Pizzoccaro, Anne, Francois, Amaury, Ling, Bing, Maffre, Violette, Couette, Brigitte, Busserolles, Jérôme, Courteix, Christine, Noel, Jacques, Lazdunski, Michel, Eschalier, Alain, Authier, Nicolas, Bourinet, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377073/
https://ncbi.nlm.nih.gov/pubmed/21438154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201100134
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