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Inferring a Transcriptional Regulatory Network from Gene Expression Data Using Nonlinear Manifold Embedding

Transcriptional networks consist of multiple regulatory layers corresponding to the activity of global regulators, specialized repressors and activators as well as proteins and enzymes shaping the DNA template. Such intrinsic complexity makes uncovering connections difficult and it calls for corresp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zare, Hossein, Kaveh, Mostafa, Khodursky, Arkady
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155518/
https://ncbi.nlm.nih.gov/pubmed/21857910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021969
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