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Regulated inactivation of the spindle assembly checkpoint without functional mitotic spindles
The spindle assembly checkpoint (SAC) arrests mitosis until bipolar attachment of spindle microtubules to all chromosomes is accomplished. However, when spindle formation is prevented and the SAC cannot be satisfied, mammalian cells can eventually overcome the mitotic arrest while the checkpoint is...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3155307/ https://ncbi.nlm.nih.gov/pubmed/21642954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.176 |
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