Dual Targeting of Tumor Angiogenesis and Chemotherapy by Endostatin-Cytosine Deaminase-Uracil Phosphoribosyl Transferase

Several antiangiogenic drugs targeting VEGF/VEGFR approved by the FDA for many cancer types including colorectal and lung cancer can effectively reduce tumor growth. However, targeting the VEGF signaling pathway will likely influence the normal function of endothelial cells in maintaining homeostasi...

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Détails bibliographiques
Auteurs principaux: Chen, Chun-Te, Yamaguchi, Hirohito, Lee, Hong-Jen, Du, Yi, Lee, Heng-Huan, Xia, Weiya, Yu, Wen-Hsuan, Hsu, Jennifer L., Yen, Chia-Jui, Sun, Hui-Lung, Wang, Yan, Yeh, Edward T. H., Hortobagyi, Gabriel N., Hung, Mien-Chie
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155219/
https://ncbi.nlm.nih.gov/pubmed/21610170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-1117
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