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Organotins Are Potent Activators of PPARγ and Adipocyte Differentiation in Bone Marrow Multipotent Mesenchymal Stromal Cells

Adipocyte differentiation in bone marrow is potentially deleterious to both bone integrity and lymphopoiesis. Here, we examine the hypothesis that organotins, common environmental contaminants that are dual ligands for peroxisome proliferator–activated receptor (PPAR) γ and its heterodimerization pa...

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Autors principals: Yanik, Susan C., Baker, Amelia H., Mann, Koren K., Schlezinger, Jennifer J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155090/
https://ncbi.nlm.nih.gov/pubmed/21622945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr140
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