Epigenetic Mechanisms of Mouse Interstrain Variability in Genotoxicity of the Environmental Toxicant 1,3-Butadiene

1,3-Butadiene (BD) is a common environmental contaminant classified as “carcinogenic to humans.” Formation of BD-induced DNA adducts plays a major role in its carcinogenicity. BD is also an epigenotoxic agent (i.e., it affects DNA and histone methylation in the liver). We used a panel of genetically...

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Autors principals: Koturbash, Igor, Scherhag, Anne, Sorrentino, Jessica, Sexton, Kenneth, Bodnar, Wanda, Swenberg, James A., Beland, Frederick A., Pardo-Manuel deVillena, Fernando, Rusyn, Ivan, Pogribny, Igor P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Molecular Toxicology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155089/
https://ncbi.nlm.nih.gov/pubmed/21602187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr133
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