cAMP-Dependent Cytosolic Mislocalization of p27(kip)-Cyclin D1 During Quinol-Thioether–Induced Tuberous Sclerosis Renal Cell Carcinoma

The loss of tuberin, the tuberous sclerosis-2 (Tsc-2) gene product, is associated with cytoplasmic mislocalization of p27 in uterine leiomyomas derived from Eker rats (Tsc-2(EK/+)) and in human metastatic renal cell carcinoma tissue. Signaling associated with cytoplasmic mislocalization of p27 in re...

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Detalhes bibliográficos
Main Authors: Cohen, Jennifer D., Tham, Kimberly Y., Mastrandrea, Nicholas J., Gallegos, Alfred C., Monks, Terrence J., Lau, Serrine S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Carcinogenicity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155088/
https://ncbi.nlm.nih.gov/pubmed/21693435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr118
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