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Reduction of Reactive Oxygen Species Prevents Hypoxia-Induced CREB Depletion in Pulmonary Artery Smooth Muscle Cells

Hypoxia-induced pulmonary arterial hypertension (PAH) is a deadly disease characterized by progressive remodeling and persistent vasoconstriction of the pulmonary arterial (PA) system. Remodeling of the PA involves smooth muscle cell (SMC) proliferation, hypertrophy, migration and elevated extracell...

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Detalhes bibliográficos
Main Authors: Klemm, Dwight J., Majka, Susan M., Crossno, Joseph T., Psilas, John C., Reusch, Jane E.B., Garat, Chrystelle V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155008/
https://ncbi.nlm.nih.gov/pubmed/21562428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e31821f2773
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