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Pyrrolinne-pyrrolidine Oligomers As Universal Peptidomimetics
Peptidomimetics 1 – 3 were prepared from aminoacid-derived tetramic acids 7 as the key starting materials. Calculations show that preferred conformations of 1 can align their side-chain vectors with amino acids in common secondary structures more effectively than 3. A good fit was found for a prefer...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154983/ https://ncbi.nlm.nih.gov/pubmed/21780756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2033734 |
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