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Pyrrole-based Scaffolds For Turn Mimics
[Image: see text] Two amino acid derived synthons were combined to give homopropargylic amines 2. Platinum dichloride was used to cyclize these intermediates into pyrroles 3 which collapsed to the target secondary structure mimics 1 on treatment with base. Side chains of these compounds overlay with...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3077957/ https://ncbi.nlm.nih.gov/pubmed/21268601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol103022m |
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