The landscape of recombination in African Americans

Recombination, together with mutation, is the ultimate source of genetic variation in populations. We leverage the recent mixture of people of African and European ancestry in the Americas to build a genetic map measuring the probability of crossing-over at each position in the genome, based on abou...

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Huvudupphovsmän: Hinch, Anjali G., Tandon, Arti, Patterson, Nick, Song, Yunli, Rohland, Nadin, Palmer, Cameron D., Chen, Gary K., Wang, Kai, Buxbaum, Sarah G., Akylbekova, Meggie, Aldrich, Melinda C., Ambrosone, Christine B., Amos, Christopher, Bandera, Elisa V., Berndt, Sonja I., Bernstein, Leslie, Blot, William J., Bock, Cathryn H., Boerwinkle, Eric, Cai, Qiuyin, Caporaso, Neil, Casey, Graham, Cupples, L. Adrienne, Deming, Sandra L., Diver, W. Ryan, Divers, Jasmin, Fornage, Myriam, Gillanders, Elizabeth M., Glessner, Joseph, Harris, Curtis C., Hu, Jennifer J., Ingles, Sue A., Isaacs, Williams, John, Esther M., Kao, W. H. Linda, Keating, Brendan, Kittles, Rick A., Kolonel, Laurence N., Larkin, Emma, Le Marchand, Loic, McNeill, Lorna H., Millikan, Robert C., Murphy, Adam, Musani, Solomon, Neslund-Dudas, Christine, Nyante, Sarah, Papanicolaou, George J., Press, Michael F., Psaty, Bruce M., Reiner, Alex P., Rich, Stephen S., Rodriguez-Gil, Jorge L., Rotter, Jerome I., Rybicki, Benjamin A., Schwartz, Ann G., Signorello, Lisa B., Spitz, Margaret, Strom, Sara S., Thun, Michael J., Tucker, Margaret A., Wang, Zhaoming, Wiencke, John K., Witte, John S., Wrensch, Margaret, Wu, Xifeng, Yamamura, Yuko, Zanetti, Krista A., Zheng, Wei, Ziegler, Regina G., Zhu, Xiaofeng, Redline, Susan, Hirschhorn, Joel N., Henderson, Brian E., Taylor, Herman A., Price, Alkes L., Hakonarson, Hakon, Chanock, Stephen J., Haiman, Christopher A., Wilson, James G., Reich, David, Myers, Simon R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154982/
https://ncbi.nlm.nih.gov/pubmed/21775986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10336
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