Genome-wide Scan of 29,141 African Americans Finds No Evidence of Directional Selection since Admixture

The extent of recent selection in admixed populations is currently an unresolved question. We scanned the genomes of 29,141 African Americans and failed to find any genome-wide-significant deviations in local ancestry, indicating no evidence of selection influencing ancestry after admixture. A recen...

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Detalhes bibliográficos
Main Authors: Bhatia, Gaurav, Tandon, Arti, Patterson, Nick, Aldrich, Melinda C., Ambrosone, Christine B., Amos, Christopher, Bandera, Elisa V., Berndt, Sonja I., Bernstein, Leslie, Blot, William J., Bock, Cathryn H., Caporaso, Neil, Casey, Graham, Deming, Sandra L., Diver, W. Ryan, Gapstur, Susan M., Gillanders, Elizabeth M., Harris, Curtis C., Henderson, Brian E., Ingles, Sue A., Isaacs, William, De Jager, Phillip L., John, Esther M., Kittles, Rick A., Larkin, Emma, McNeill, Lorna H., Millikan, Robert C., Murphy, Adam, Neslund-Dudas, Christine, Nyante, Sarah, Press, Michael F., Rodriguez-Gil, Jorge L., Rybicki, Benjamin A., Schwartz, Ann G., Signorello, Lisa B., Spitz, Margaret, Strom, Sara S., Tucker, Margaret A., Wiencke, John K., Witte, John S., Wu, Xifeng, Yamamura, Yuko, Zanetti, Krista A., Zheng, Wei, Ziegler, Regina G., Chanock, Stephen J., Haiman, Christopher A., Reich, David, Price, Alkes L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185117/
https://ncbi.nlm.nih.gov/pubmed/25242497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.08.011
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