Drug-Resistant Genotypes and Multi-Clonality in Plasmodium falciparum Analysed by Direct Genome Sequencing from Peripheral Blood of Malaria Patients

Naturally acquired blood-stage infections of the malaria parasite Plasmodium falciparum typically harbour multiple haploid clones. The apparent number of clones observed in any single infection depends on the diversity of the polymorphic markers used for the analysis, and the relative abundance of r...

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Autori principali: Robinson, Timothy, Campino, Susana G., Auburn, Sarah, Assefa, Samuel A., Polley, Spencer D., Manske, Magnus, MacInnis, Bronwyn, Rockett, Kirk A., Maslen, Gareth L., Sanders, Mandy, Quail, Michael A., Chiodini, Peter L., Kwiatkowski, Dominic P., Clark, Taane G., Sutherland, Colin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154926/
https://ncbi.nlm.nih.gov/pubmed/21853089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023204
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