B Cell Repertoire Analysis Identifies New Antigenic Domains on Glycoprotein B of Human Cytomegalovirus which Are Target of Neutralizing Antibodies

Human cytomegalovirus (HCMV), a herpesvirus, is a ubiquitously distributed pathogen that causes severe disease in immunosuppressed patients and infected newborns. Efforts are underway to prepare effective subunit vaccines and therapies including antiviral antibodies. However, current vaccine efforts...

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Main Authors: Pötzsch, Sonja, Spindler, Nadja, Wiegers, Anna-Katharina, Fisch, Tanja, Rücker, Pia, Sticht, Heinrich, Grieb, Nina, Baroti, Tina, Weisel, Florian, Stamminger, Thomas, Martin-Parras, Luis, Mach, Michael, Winkler, Thomas H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154849/
https://ncbi.nlm.nih.gov/pubmed/21852946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002172
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