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Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT(1B) and 5-HT(1F) receptors

Sensory afferent transmission and associated spinal reflexes are normally inhibited by serotonin (5-HT) derived from the brain stem. Spinal cord injury (SCI) that eliminates this 5-HT innervation leads to a disinhibition of sensory transmission and a consequent emergence of unusually long polysynapt...

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Detalhes bibliográficos
Main Authors: Murray, Katherine C., Stephens, Marilee J., Rank, Michelle, D'Amico, Jessica, Gorassini, Monica A., Bennett, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154834/
https://ncbi.nlm.nih.gov/pubmed/21653728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01011.2010
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