Eosinophils generate brominating oxidants in allergen-induced asthma

Eosinophils promote tissue injury and contribute to the pathogenesis of allergen-triggered diseases like asthma, but the chemical basis of damage to eosinophil targets is unknown. We now demonstrate that eosinophil activation in vivo results in oxidative damage of proteins through bromination of tyr...

Celý popis

Podrobná bibliografie

Vydáno v:	J Clin Invest
Hlavní autoři:	Wu, Weijia, Samoszuk, Michael K., Comhair, Suzy A.A., Thomassen, Mary Jane, Farver, Carol F., Dweik, Raed A., Kavuru, Mani S., Erzurum, Serpil C., Hazen, Stanley L.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 2000
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315470/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811853/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9702
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!