Levosimendan restores the positive force-frequency relation in heart failure

Frequency potentiation of contractile function is a major mechanism of the increase in myocardial performance during exercise. In heart failure (HF), this positive force-frequency relation is impaired, and the abnormal left ventricular (LV)-arterial coupling is exacerbated by tachycardia. A myofilam...

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Hlavní autoři: Masutani, Satoshi, Cheng, Heng-Jie, Tachibana, Hideo, Little, William C., Cheng, Che-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
Muscle Mechanics and Ventricular Function
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154658/
https://ncbi.nlm.nih.gov/pubmed/21572004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01116.2010
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