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Levosimendan restores the positive force-frequency relation in heart failure
Frequency potentiation of contractile function is a major mechanism of the increase in myocardial performance during exercise. In heart failure (HF), this positive force-frequency relation is impaired, and the abnormal left ventricular (LV)-arterial coupling is exacerbated by tachycardia. A myofilam...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154658/ https://ncbi.nlm.nih.gov/pubmed/21572004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01116.2010 |
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