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C-Type Natriuretic Peptide Improves Left Ventricular Functional Performance at Rest and Restores Normal Exercise Responses after Heart Failure

In heart failure (HF), the impaired left ventricular (LV) arterial coupling and diastolic dysfunction present at rest are exacerbated during exercise. C-type natriuretic peptide (CNP) is elevated in HF; however, its functional effects are unclear. We tested the hypotheses that CNP with vasodilating,...

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Détails bibliographiques
Publié dans:J Pharmacol Exp Ther
Auteurs principaux: Li, Tiankai, Cheng, Heng-Jie, Ohte, Nobuyuki, Hasegawa, Hiroshi, Morimoto, Atsushi, Herrington, David M., Little, William C., Li, Weimin, Cheng, Che Ping
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885509/
https://ncbi.nlm.nih.gov/pubmed/27026682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.231696
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