C-Type Natriuretic Peptide Improves Left Ventricular Functional Performance at Rest and Restores Normal Exercise Responses after Heart Failure

In heart failure (HF), the impaired left ventricular (LV) arterial coupling and diastolic dysfunction present at rest are exacerbated during exercise. C-type natriuretic peptide (CNP) is elevated in HF; however, its functional effects are unclear. We tested the hypotheses that CNP with vasodilating,...

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Detalles Bibliográficos
Publicado en:J Pharmacol Exp Ther
Main Authors: Li, Tiankai, Cheng, Heng-Jie, Ohte, Nobuyuki, Hasegawa, Hiroshi, Morimoto, Atsushi, Herrington, David M., Little, William C., Li, Weimin, Cheng, Che Ping
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Cardiovascular
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885509/
https://ncbi.nlm.nih.gov/pubmed/27026682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.231696
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