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Inhibition of neutrophil apoptosis by PAI-1

Increased circulating and tissue levels of plasminogen activator inhibitor 1 (PAI-1) are often present in severe inflammatory states associated with neutrophil activation and accumulation and correlate with poor clinical outcome from many of these conditions. The mechanisms by which PAI-1 contribute...

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Autori principali: Zmijewski, Jaroslaw W., Bae, Hong-Beom, Deshane, Jessy S., Peterson, Cynthia B., Chaplin, David D., Abraham, Edward
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154633/
https://ncbi.nlm.nih.gov/pubmed/21622848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00075.2011
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