CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo

Hypertrophic growth is an adaptive response of the heart to diverse pathological stimuli and is characterized by cardiomyocyte enlargement, sarcomere assembly, and activation of a fetal program of cardiac gene expression. A variety of Ca(2+)-dependent signal transduction pathways have been implicate...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Passier, Robert, Zeng, Hong, Frey, Norbert, Naya, Francisco J., Nicol, Rebekka L., McKinsey, Timothy A., Overbeek, Paul, Richardson, James A., Grant, Stephen R., Olson, Eric N.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC315462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8551
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