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Regulation of Kir4.1 and AQP4 expression and stability at the basolateral domain of epithelial MDCK cells by the extracellular matrix

The proper targeting of ion channels to specialized domains is crucial for cell function. Kir4.1, the inwardly rectifying potassium channel, and aquaporin-4 (AQP4), the type 4 water-permeable channel, are localized at the basolateral domain of polarized epithelial cells; however, the mechanisms invo...

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Главные авторы: Tham, Daniel Kai Long, Moukhles, Hakima
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154586/
https://ncbi.nlm.nih.gov/pubmed/21543416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00315.2010
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