Endothelin-1 contributes to increased NFATc3 activation by chronic hypoxia in pulmonary arteries

Chronic hypoxia (CH) activates the Ca(2+)-dependent transcription factor nuclear factor of activated T cells isoform c3 (NFATc3) in mouse pulmonary arteries. However, the mechanism of this response has not been explored. Since we have demonstrated that NFATc3 is required for CH-induced pulmonary art...

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Bibliographic Details
Main Authors: de Frutos, Sergio, Ramiro Diaz, Juan Manuel, Nitta, Carlos H., Sherpa, Mingma L., Gonzalez Bosc, Laura V.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2011
Subjects:
Vascular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154561/
https://ncbi.nlm.nih.gov/pubmed/21525433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00029.2011
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