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Regulation of soluble guanylyl cyclase-α1 expression in chronic hypoxia-induced pulmonary hypertension: role of NFATc3 and HuR

The nitric oxide/soluble guanylyl cyclase (sGC) signal transduction pathway plays an important role in smooth muscle relaxation and phenotypic regulation. However, the transcriptional regulation of sGC gene expression is largely unknown. It has been shown that sGC expression increases in pulmonary a...

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Main Authors: de Frutos, Sergio, Nitta, Carlos H., Caldwell, Elizabeth, Friedman, Jessica, González Bosc, Laura V.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739769/
https://ncbi.nlm.nih.gov/pubmed/19592461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00060.2009
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