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Membrane cholesterol modulates the fluid shear stress response of polymorphonuclear leukocytes via its effects on membrane fluidity

Continuous exposure of polymorphonuclear leukocytes (PMNLs) to circulatory hemodynamics points to fluid flow as a biophysical regulator of their activity. Specifically, fluid flow-derived shear stresses deactivate leukocytes via actions on the conformational activities of proteins on the cell surfac...

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Detalles Bibliográficos
Main Authors: Zhang, Xiaoyan, Hurng, Jonathan, Rateri, Debra L., Daugherty, Alan, Schmid-Schönbein, Geert W., Shin, Hainsworth Y.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154559/
https://ncbi.nlm.nih.gov/pubmed/21525434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00458.2010
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