A role for heterologous gap junctions between melanoma and endothelial cells in metastasis

F10 and BL6 sublines of B16 mouse melanoma cells are metastatic after intravenous injection, but only BL6 cells are metastatic after subcutaneous injection. We found that connexin (Cx) 26 is upregulated in BL6 cells. To examine gap junction formation, we devised a coculture system, in which an opene...

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Detalhes bibliográficos
Main Authors: Ito, Akihiko, Katoh, Fumitaka, Kataoka, Tatsuki R., Okada, Morihito, Tsubota, Noriaki, Asada, Hideo, Yoshikawa, Kunihiko, Maeda, Sakan, Kitamura, Yukihiko, Yamasaki, Hiroshi, Nojima, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC315440/
https://ncbi.nlm.nih.gov/pubmed/10791993
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