A Truncated Isoform of the Protein Phosphatase 2A B56γ Regulatory Subunit May Promote Genetic Instability and Cause Tumor Progression

F10, a subline of the B16 mouse melanoma cell line, is itself the parent of the more metastatic BL6 line. BL6 cells differ from F10 cells by an alteration of the gene encoding the B56γ regulatory subunit of protein phosphatase 2A (PP2A), which results in the expression of a truncated variant of the...

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Bibliografske podrobnosti
Main Authors: Ito, Akihiko, Koma, Yu-ichiro, Watabe, Kenji, Nagano, Teruaki, Endo, Yuichi, Nojima, Hiroshi, Kitamura, Yukihiko
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2003
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851121/
https://ncbi.nlm.nih.gov/pubmed/12507892
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