Specificity of RSG-1.2 Peptide Binding to RRE-IIB RNA Element of HIV-1 over Rev Peptide Is Mainly Enthalpic in Origin

Rev is an essential HIV-1 regulatory protein which binds to the Rev responsive element (RRE) present within the env gene of HIV-1 RNA genome. This binding facilitates the transport of the RNA to the cytoplasm, which in turn triggers the switch between viral latency and active viral replication. Esse...

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Bibliographic Details
Main Authors: Kumar, Santosh, Bose, Debojit, Suryawanshi, Hemant, Sabharwal, Harshana, Mapa, Koyeli, Maiti, Souvik
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154333/
https://ncbi.nlm.nih.gov/pubmed/21853108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023300
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