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ADP-Ribosylation Factor 6 Mediates E-Cadherin Recovery by Chemical Chaperones
E-cadherin plays a powerful tumor suppressor role. Germline E-cadherin mutations justify 30% of Hereditary Diffuse Gastric Cancer (HDGC) and missense mutations are found in 30% of these families. We found possible to restore in vitro mutant E-cadherin associated to HDGC syndrome by using Chemical Ch...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154279/ https://ncbi.nlm.nih.gov/pubmed/21853084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023188 |
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