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E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion

BACKGROUND: E7080 is an orally active multi-targeted kinase inhibitor whose targets include vascular endothelial growth factor receptors (VEGFR), fibroblast growth factor receptor (FGFR) and platelet derived growth factor receptors (PDGFR). It has been shown to inhibit tumor angiogenesis by targetin...

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Detalhes bibliográficos
Main Authors: Glen, Hilary, Mason, Susan, Patel, Hitesh, Macleod, Kenneth, Brunton, Valerie G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154179/
https://ncbi.nlm.nih.gov/pubmed/21781317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-309
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