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Single Genome Sequencing of HIV -1 Gag and Protease to Assess Protease Inhibitor Resistance at Virologic Failure of Simplified vs. Standard Maintenance Therapy with Lopinavir/Ritonavirin the OK04 Trial

BACKGROUND: Ritonavir -boosted lopinavir (LPV/RTV) alone has been evaluated as simplified maintenance therapy for HIV -1 infection, but there are concerns about greater potential for emergence of protease inhibitor (PI) resistance. The OK04 trial evaluated maintenance therapy with LPV/RTV alone vers...

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Detalhes bibliográficos
Main Authors: McKinnon, John E., Delgado, Rafael, Pulido, Fede rico, Shao, Wei, Arribas, Jose R., Mellors, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154069/
https://ncbi.nlm.nih.gov/pubmed/21817194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP1812
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