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Single Genome Sequencing of HIV -1 Gag and Protease to Assess Protease Inhibitor Resistance at Virologic Failure of Simplified vs. Standard Maintenance Therapy with Lopinavir/Ritonavirin the OK04 Trial
BACKGROUND: Ritonavir -boosted lopinavir (LPV/RTV) alone has been evaluated as simplified maintenance therapy for HIV -1 infection, but there are concerns about greater potential for emergence of protease inhibitor (PI) resistance. The OK04 trial evaluated maintenance therapy with LPV/RTV alone vers...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154069/ https://ncbi.nlm.nih.gov/pubmed/21817194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP1812 |
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