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Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models

Zebrafish models of human neuropsychiatric diseases offer opportunities to identify novel therapeutic targets and treatments through phenotype-based genetic or chemical modifier screens. In order to develop an assay to detect rescue of zebrafish models of Parkinsonism, we characterized spontaneous z...

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Detalhes bibliográficos
Main Authors: Farrell, Thomas C., Cario, Clinton L., Milanese, Chiara, Vogt, Andreas, Jeong, Jong-Hyeon, Burton, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153634/
https://ncbi.nlm.nih.gov/pubmed/21669287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.05.016
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