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Including Total EGFR Staining in Scoring Improves EGFR Mutations Detection by Mutation-Specific Antibodies and EGFR TKIs Response Prediction

Epidermal growth factor receptor (EGFR) is a novel target for therapy in subsets of non-small cell lung cancer, especially adenocarcinoma. Tumors with EGFR mutations showed good response to EGFR tyrosine kinase inhibitors (TKIs). We aimed to identify the discriminating capacity of immunohistochemica...

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Bibliografske podrobnosti
Main Authors: Wu, Shang-Gin, Chang, Yih-Leong, Lin, Jou-Wei, Wu, Chen-Tu, Chen, Hsuan-Yu, Tsai, Meng-Feng, Lee, Yung-Chie, Yu, Chong-Jen, Shih, Jin-Yuan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153495/
https://ncbi.nlm.nih.gov/pubmed/21858063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023303
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