Lhx6 and Lhx8 Coordinately Induce Neuronal Expression of Shh that Controls the Generation of Interneuron Progenitors

Lhx6 and Lhx8 transcription factor coexpression in early-born MGE neurons is required to induce neuronal Shh expression. We provide evidence that these transcription factors regulate expression of a Shh enhancer in MGE neurons. Lhx6 and Lhx8 are also required to prevent Nkx2-1 expression in a subset...

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Autores principales: Flandin, Pierre, Zhao, Yangu, Vogt, Daniel, Jeong, Juhee, Long, Jason, Potter, Gregory, Westphal, Heiner, Rubenstein, John L.R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153409/
https://ncbi.nlm.nih.gov/pubmed/21658586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.04.020
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