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Intra-axonal translation and retrograde trafficking of CREB promotes neuronal survival

During development of the nervous system, axons and growth cones contain mRNAs, such as β-actin, cofilin, and RhoA, that are locally translated in response to guidance cues. Intra-axonal translation of these mRNAs results in local morphological responses, however other functions of intra-axonal mRNA...

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Detalhes bibliográficos
Main Authors: Cox, Llewellyn J., Hengst, Ulrich, Gurskaya, Nadya., Lukyanov, Konstantin A., Jaffrey, Samie R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153364/
https://ncbi.nlm.nih.gov/pubmed/18193038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1677
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