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Outsourcing CREB translation to axons to survive

Nerve growth factor induces sensory neuron survival via retrograde signalling from the axon to the cell body. Local translation of the transcription factor CREB in the axon, followed by its transport to the nucleus, is involved in this process.

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Detalhes bibliográficos
Main Authors: Lin, Andrew C., Holt, Christine E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682635/
https://ncbi.nlm.nih.gov/pubmed/18246035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb0208-115
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