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Progressive Ankylosis Protein (ANK) in Osteoblasts and Osteoclasts Controls Bone Formation and Bone Remodeling

The progressive ankylosis gene (ank) encodes a transmembrane protein that transports intracellular inorganic pyrophosphate (PP(i)) to the extracellular milieu. ank/ank mice, which express a truncated nonfunctional ANK, showed a markedly reduced bone mass, bone-formation rate, and number of tartrate-...

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Autors principals: Kim, Hyon Jong, Minashima, Takeshi, McCarthy, Edward F, Winkles, Jeffrey A, Kirsch, Thorsten
Format: Artigo
Idioma:Inglês
Publicat: Wiley Subscription Services, Inc., A Wiley Company 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153348/
https://ncbi.nlm.nih.gov/pubmed/20200976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.60
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