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Consequences and Utility of the Zinc-Dependent Metalloprotease Activity of Anthrax Lethal Toxin

Anthrax is caused by the gram-positive bacterium Bacillus anthracis. The pathogenesis of this disease is dependent on the presence of two binary toxins, edema toxin (EdTx) and lethal toxin (LeTx). LeTx, the major virulence factor contributing to anthrax, contains the effector moiety lethal factor (L...

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Autors principals: Bromberg-White, Jennifer, Lee, Chih-Shia, Duesbery, Nicholas
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153234/
https://ncbi.nlm.nih.gov/pubmed/22069624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins2051038
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