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The Zinc-Dependent Protease Activity of the Botulinum Neurotoxins

The botulinum neurotoxins (BoNT, serotypes A-G) are some of the most toxic proteins known and are the causative agents of botulism. Following exposure, the neurotoxin binds and enters peripheral cholinergic nerve endings and specifically and selectively cleaves one or more SNARE proteins to produce...

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Détails bibliographiques
Auteurs principaux: Lebeda, Frank J., Cer, Regina Z., Mudunuri, Uma, Stephens, Robert, Singh, Bal Ram, Adler, Michael
Format: Artigo
Langue:Inglês
Publié: MDPI 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153231/
https://ncbi.nlm.nih.gov/pubmed/22069621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins2050978
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