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The Zinc-Dependent Protease Activity of the Botulinum Neurotoxins

The botulinum neurotoxins (BoNT, serotypes A-G) are some of the most toxic proteins known and are the causative agents of botulism. Following exposure, the neurotoxin binds and enters peripheral cholinergic nerve endings and specifically and selectively cleaves one or more SNARE proteins to produce...

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Bibliografiske detaljer
Main Authors: Lebeda, Frank J., Cer, Regina Z., Mudunuri, Uma, Stephens, Robert, Singh, Bal Ram, Adler, Michael
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153231/
https://ncbi.nlm.nih.gov/pubmed/22069621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins2050978
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