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Vandetanib (ZD6474) in the Treatment of Medullary Thyroid Cancer

Vandetanib (ZD6474) is an orally bioavailable small molecule tyrosine kinase inhibitor of multiple growth factor receptors, including RET (Rearrange during transfection), vascular endothelial growth factor receptor-2 (VEGFR-2) and epidermal growth factor receptor (EGFR). The activity against RET and...

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Bibliographic Details
Main Authors: Deshpande, Hari, Roman, Sanziana, Thumar, Jaykumar, Sosa, Julie Ann
Format: Artigo
Language:Inglês
Published: Libertas Academica 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3153121/
https://ncbi.nlm.nih.gov/pubmed/21836817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMO.S6197
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