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Current status of vandetanib (ZD6474) in the treatment of non-small cell lung cancer

Vandetanib (ZD6474) is an oral small molecule inhibitor of multiple intracellular receptor kinases, including the vascular endothelial growth factor receptor (VEGFR) -2 and epidermal growth factor receptor (EGFR). Both VEGFR and EGFR pathways have emerged as instrumental in the growth and metastasis...

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Bibliografiska uppgifter
Huvudupphovsmän: Flanigan, Jaclyn, Deshpande, Hari, Gettinger, Scott
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943196/
https://ncbi.nlm.nih.gov/pubmed/20859451
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